Extensive bulky endometriosis may also be present in the uterine muscle itself, where it is called adenomyosis. Less commonly involved areas include the anterior cul-de-sac (the area above the bladder and the anterior uterus), the appendix, and the small bowel. One or both pelvic sidewalls overlying the ureters and the rectosigmoid are often affected. The lesions can often obliterate the normal anatomy of the cul-de-sac, with the rectum sticking to the posterior vagina, cervix, and uterine fundus. Histopathologic examination to document endometriotic glands and stroma is necessary to substantiate a diagnosis of the endometriosis in any suspect lesion.Įxtensive endometriosis usually involves the posterior cul-de-sac of Douglas, the area surrounded posteriorly by the anterior rectum, anteriorly by the posterior vagina and cervix, and laterally by the uterosacral ligaments. They represent a long-standing chronic inflammatory response. These nodules consist of endometriotic glands and stroma surrounded by fibromuscular tissue that have accumulated over many years in response to cyclic monthly activation of the endometriosis. Extensive endometriosis refers to bulky deep fibrotic endometriosis deposits that can often be palpated preoperatively as tender pelvic nodules. The ovaries, the posterior leaf of the broad ligament, and the cul-de-sac of Douglas behind the uterus are the most common locations of endometriosis, and the left side is more frequently affected than the right, as the recto sigmoid and its mesocolon - both often involved with endometriosis - enter the pelvis from the left side (Redwine,1987 Vercellini et al,1998). The most common presentations of endometriosis include pelvic pain, infertility, and adnexal mass. Therefore, the laparoscopist must be thoroughly familiar with the current standards of diagnosis and management of this complex disease. ![]() Back up save files, delete the game and reinstall it ![]() Right-click Dungrid -> Properties -> Local Files -> click the Verify integrity of game files.Ħ. Check that the external graphics card is working normally.ĥ. (For laptop) Check if the power is connectedĤ. Check if the Windows version is updated to the latest versionģ. Check if the internal and external graphics drivers are updated to the latest versionĢ. If the game does not run or crashes, please check the following items first.ġ. Steam / steamapps / common / Dungreed / Dungreed_Data / output_log.txt ![]() ![]() If you report a bug with a comment in the update news, it's hard to get a quick response. Please send log files and screenshots to in case of other bugs besides the ones below. We are constantly looking for solutions to common bugs and crashes. Thank you so much for playing with Dungreed and reporting to us.ĭiscussion topics are checking all posts, whether they are commented or not.
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